Fan, Guoping, Ph.D.

Research

Molecular and cellular mechanisms underlying neural development

Appointments

• Professor, Human Genetics
• Member, Bioinformatics GPB Home Area
• Brain Research Institute
• Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
• Gene Regulation GPB Home Area
• Genetics & Genomics GPB Home Area
• JCCC Gene Regulation Program Area
• Neuroscience GPB Home Area

Appointments

His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.

Publications

1. Liu, H, Li, H, Tian, B, Jiang, Y, Li, Z, Sun, Z et al.. Alterations in the DTI-ALPS index and choroid plexus volume as brain-immune interfacing indicators in neuropsychiatric lupus erythematosus with inflammatory phenotype. Lupus Sci Med. 2026;13 (1):. doi: 10.1136/lupus-2025-001815. PubMed PMID:41605603 .
2. Yin, L, Li, B, Wei, Y, Li, Z, Yang, Y, Zhang, J et al.. SUZ12 promotes pancreatic ductal adenocarcinoma progression and chemoresistance by epigenetically silencing NCOA4-induced ferroptosis. Acta Biochim Biophys Sin (Shanghai). 2026; :. doi: 10.3724/abbs.2025215. PubMed PMID:41601257 .
3. Wang, X, Yan, W, Fan, G, Han, Z, Xia, M, Liu, J et al.. Earthworms reduce the accumulation of soil-borne pathogens in strawberry by altering the gut microbiome and physiological characteristics. Ecotoxicol Environ Saf. 2026;309 :119595. doi: 10.1016/j.ecoenv.2025.119595. PubMed PMID:41601032 .
4. Niyaz, A, Nasir, M, Zhang, S, Wang, S, Min, C, Fan, G et al.. Optimal Branch Bending Angle for Korla Fragrant Pear: A Multi-Trait Physiological Trade-Off Framework. Plants (Basel). 2026;15 (2):. doi: 10.3390/plants15020339. PubMed PMID:41600146 PubMed Central PMC12845164.
5. Wang, T, Ma, J, Zhong, Y, Liu, S, Cui, W, Liu, X et al.. Study of Fermentation Conditions Optimization for Xylanase Production by Aspergillus tubingensis FS7Y52 and Application in Agricultural Wastes Degradation. Foods. 2026;15 (2):. doi: 10.3390/foods15020399. PubMed PMID:41596999 PubMed Central PMC12840682.

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