Research
Functional magnetic resonance imaging, language, memory
Appointments
- Clinical Neuropsychologist, Resnick Neuropsychiatric Hospital
- Professor, Psychiatry and Biobehavioral Sciences
- Center for Autism Research and Treatment (CART)
- Staglin Center for Cognitive Neuroscience
- Professor in Residence, Cognitive Psychology
- Tennenbaum Center for the Biology of Creativity
- Member, Brain Research Institute
- Neuroengineering Training Program
- Neuroscience GPB Home Area
Biography
Dr. Bookheimer’s research examines the neuroanatomy of higher cognitive functions- specifically, understanding how memory and language functions are organized in the human brain in health and disease.
The laboratory focuses on functional neuroimaging techniques (functional magnetic resonance imaging, Positron Emission Tomography, and optical intrinsic signal imaging), in combination with invasive techniques (electrocorticography and intracarotid amobarbitol (Wada) testing ) to develop an integrated knowledge of language and memory representations in normal humans and those with neurological and psychiatric disorders affecting language and memory.
A large focus of research activity involves developing this new technology into tools that can benefit patients with developmental and neurological disorders.
Publications
- Arutiunian, V, Santhosh, M, Neuhaus, E, Borland, H, Bernier, RA, Bookheimer, SY et al.. Altered aperiodic EEG spectral power during speech perception task is associated with verbal communication in youths with Autism Spectrum Disorder. bioRxiv. 2025; :. doi: 10.64898/2025.12.29.696902. PubMed PMID:41509301 PubMed Central PMC12776406.
- Spivak, NM, Bishay, AAED, Haroon, J, Hopkins, AR, Tanabe, J, Halavi, S et al.. Dose-Escalation Study of Amygdalar Transcranial Focused Ultrasound in Healthy Volunteers. medRxiv. 2025; :. doi: 10.1101/2025.10.21.25338018. PubMed PMID:41282732 PubMed Central PMC12636638.
- M Shama, D, Su, M, Beeler-Duden, S, Bernier, RA, Bookheimer, SY, Dapretto, M et al.. Harnessing Trial-to-Trial Variability of EEG Spectral Characteristics to Understand Autism. J Autism Dev Disord. 2025; :. doi: 10.1007/s10803-025-07125-y. PubMed PMID:41273602 .
- Bramen, JE, Siddarth, P, Popa, ES, Kress, GT, Rapozo, MK, Hodes, JF et al.. A multi-modal medical management and lifestyle intervention increase cerebral blood flow and lowers diabetic risk in persons with early Alzheimer's disease: Mid-trial results from the PREVENTION trial. J Alzheimers Dis. 2025;108 (4):1819-1833. doi: 10.1177/13872877251388933. PubMed PMID:41243261 PubMed Central PMC12715032.
- Arutiunian, V, Opdahl, M, Sullivan, CAW, Santhosh, M, Neuhaus, E, Borland, H et al.. Number of Alpha Peaks in the Electroencephalogram Is Associated With Clinical Phenotype and Copy Number Variants in Youths With Autism. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025; :. doi: 10.1016/j.bpsc.2025.10.001. PubMed PMID:41101705 .