Research
Hypoxic-ischemic brain injury; Fetal origins of adult disease
Appointments
- Department of Pediatrics
Biography
Devaskar’s laboratory is focused on determining the role of glucose transporters in mediating neuronal function. This is being pursued by the generation of various transgenic and knock out mouse models and phenotypic characterization.
The second area is around delineating the role of hypothalamic leptin resistance during development in the future development of obesity, providing mechanisms towards the theory of “fetal origins of adult disease”. Various signal transduction pathways are being examined and dysregulation of these pathways contributing towards the subsequent development of obesity are being explored.
Publications
- Meng, Q, Mitra, S, Del Rosario, I, Jerrett, M, Janzen, C, Devaskar, SU et al.. Urinary polycyclic aromatic hydrocarbon metabolites and their association with oxidative stress among pregnant women in Los Angeles. Environ Health. 2024;23 (1):68. doi: 10.1186/s12940-024-01107-w. PubMed PMID:39138494 PubMed Central PMC11321171.
- Ganguly, A, Ghosh, S, Jin, P, Wadehra, M, Devaskar, SU. Omega-3 reverses the metabolic and epigenetically regulated placental phenotype acquired from preconceptional and peri-conceptional exposure to air pollutants. J Nutr Biochem. 2024;134 :109735. doi: 10.1016/j.jnutbio.2024.109735. PubMed PMID:39122219 .
- Daida, T, Shin, BC, Cepeda, C, Devaskar, SU. Neurodevelopment Is Dependent on Maternal Diet: Placenta and Brain Glucose Transporters GLUT1 and GLUT3. Nutrients. 2024;16 (14):. doi: 10.3390/nu16142363. PubMed PMID:39064806 PubMed Central PMC11279700.
- Lakshminrusimha, S, Li, ST, DeLemos, CD, Moss, CR, Hoffman, J, Johnstone, L et al.. Anticipating the Effects of Accreditation Council for Graduate Medical Education-Mandated Residency Curriculum Changes on Neonatal Intensive Care Unit Staffing Models and Costs. J Pediatr. 2024; :114210. doi: 10.1016/j.jpeds.2024.114210. PubMed PMID:39053882 .
- Ghosh, S, Thamotharan, S, Fong, J, Lei, MYY, Janzen, C, Devaskar, SU et al.. Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia. Sci Rep. 2024;14 (1):16770. doi: 10.1038/s41598-024-64057-w. PubMed PMID:39039088 PubMed Central PMC11263608.