Research
Developmental neuropsychology, electrophysiology and molecular genetics
Appointments
- Associate Professor In-Residence, Psychiatry and Biobehavioral Sciences
- Brain Research Institute
- Member, Child and Adolescent Psychiatry
- Genetics & Genomics GPB Home Area
- Neuroscience GPB Home Area
- Faculty, Center for Neurobehavioral Genetics
Biography
Dr. Loo is principal investigator of two NIH grants examining the genetics of electrophysiological (EEG) measurements in attention-deficit/hyperactivity disorder (ADHD). The goal of this work is to define EEG correlates of cognitive and behavioral functioning and use these as ‘refined phenotypes’ to identify risk genes for psychiatric disorder. The long-term goal of this research is to better understand the neural mechanisms by which genetic polymorphisms produce the cognitive and behavioral phenotypes evident in childhood psychiatric disorders.
Dr. Loo’s lab is also studying cognitive and electrophysiological measures as biomarkers for treatment response in ADHD and Tourette’s Disorder. Through collaborations with other neuroscientists, protocols are being developed for the integration of EEG with cognitive and behavioral assays of inhibition and working memory as treatment outcome measures.
Publications
- Nomi, JS, Román-López, TV, Chang, FY, Friedman-Jha, A, Truong, HV, Diaz-Fong, JP et al.. Alpha-range neural oscillations are associated with multiple dynamic brain networks. bioRxiv. 2026; :. doi: 10.64898/2026.10.12.758569. PubMed PMID:42995770 PubMed Central PMC13738408.
- Chang, FY, Mao, XZ, Khalil, M, Rapport, MD, Dillon, A, Loo, SK et al.. Effects of Instructional Context on Neural Features of Attention during Learning Activities in Children with and without ADHD. bioRxiv. 2026; :. doi: 10.64898/2026.08.29.748025. PubMed PMID:42922553 PubMed Central PMC13684569.
- Wang, X, Ding, L, Meng, W, Byrnes, E, Loo, SK, Sun, S et al.. CASTOR1 functional inactivation drives KRAS-mutant NSCLC and therapy resistance by a noncanonical mechanism of tumor suppression. Sci Adv. 2026;12 (43):eaeb9836. doi: 10.1126/sciadv.aeb9836. PubMed PMID:42913021 PubMed Central PMC13693695.
- Chang, FY, Mao, XZ, Khalil, M, Rapport, MD, Dillon, A, Loo, SK et al.. Attention in laboratory tasks versus naturalistic learning contexts: Heterogeneity in measurement and mechanisms. Res Sq. 2026; :. doi: 10.21203/rs.3.rs-9511914/v1. PubMed PMID:42239791 PubMed Central PMC13228797.
- Peck, FC, Walsh, CR, Truong, H, Pochon, JF, Enriquez, KD, Bearden, CE et al.. Spectral and non-spectral EEG measures in the prediction of working memory task performance and psychopathology. bioRxiv. 2026; :. doi: 10.64898/2026.03.25.714248. PubMed PMID:41929093 PubMed Central PMC13042055.