Research
Role of serotonin in anxiety and mood disorders; human gene variants and serotonin transporter function; voltammetry; microdialysis; nanobiosensors
Appointments
- Professor, Psychiatry and Biobehavioral Sciences
- Professor in Residence, Neuroscience IDP
- Member, Brain Research Institute
- California NanoSystems Institute
- Senior Research Scientist, Hatos Center for Neuropharmacology
Biography
Dr. Andrews leads efforts in basic and translational research on anxiety and depression, and at the nexus of nanoscience and neuroscience.
Andrews’ interdisciplinary research team of neuroscientists, biologists, chemists, and engineers focuses on understanding how the serotonin system and particularly, the serotonin transporter, modulate neurotransmission to influence complex behaviors including anxiety, mood, stress responsiveness, and learning and memory.
Nanomaterials are designed for fundamental studies on neurotransmitter recognition by native and nonnative binding partners (aptamers) and for the development of in vivo nanobiosensors and functionally directed proteomics.
Publications
- Movassaghi, CS, Alcañiz Fillol, M, Kishida, KT, McCarty, G, Sombers, LA, Wassum, KM et al.. Maximizing Electrochemical Information: A Perspective on Background-Inclusive Fast Voltammetry. Anal Chem. 2024;96 (16):6097-6105. doi: 10.1021/acs.analchem.3c04938. PubMed PMID:38597398 PubMed Central PMC11044109.
- Movassaghi, CS, Andrews, AM. Call me serotonin. Nat Chem. 2024;16 (4):670. doi: 10.1038/s41557-024-01488-y. PubMed PMID:38580723 .
- Yang, K, Mitchell, NM, Banerjee, S, Cheng, Z, Taylor, S, Kostic, AM et al.. A functional group-guided approach to aptamers for small molecules. Science. 2023;380 (6648):942-948. doi: 10.1126/science.abn9859. PubMed PMID:37262137 PubMed Central PMC10686217.
- Luo, Y, Abidian, MR, Ahn, JH, Akinwande, D, Andrews, AM, Antonietti, M et al.. Technology Roadmap for Flexible Sensors. ACS Nano. 2023;17 (6):5211-5295. doi: 10.1021/acsnano.2c12606. PubMed PMID:36892156 PubMed Central PMC11223676.
- Zhao, C, Man, T, Cao, Y, Weiss, PS, Monbouquette, HG, Andrews, AM et al.. Flexible and Implantable Polyimide Aptamer-Field-Effect Transistor Biosensors. ACS Sens. 2022;7 (12):3644-3653. doi: 10.1021/acssensors.2c01909. PubMed PMID:36399772 PubMed Central PMC9982941.