Research
Neurogenetic disorders; neurobehavioral biomarkers of serious mental illness
Appointments
- Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior Brain Research Institute
- Integrative Center for Neurobehavioral Genetics
- Center for Autism Research and Treatment (CART)
- Director, Center for the Assessment and Prevention of Prodromal States (CAPPS)
Biography
Her research aims to understand genetic and neurobiological risk factors for the development of early-onset neuropsychiatric disorders. Dr. Bearden’s work examines these questions through two complementary lines of research:
1) The investigation of early biomarkers that predict disease risk and trajectory in at-risk populations; and
2) Translational approaches to understanding disrupted brain circuitry in highly penetrant genetic subtypes (e.g, 22q11.2 microdeletions)
Publications
- Guest, RM, Aberizk, K, Addington, J, Bearden, CE, Cadenhead, KS, Cannon, TD et al.. Cultural variables influence performance on the MATRICS Consensus Cognitive Battery among people at clinical high risk for psychosis. Schizophr Res. 2025;280 :60-68. doi: 10.1016/j.schres.2025.04.019. PubMed PMID:40250131 .
- Bearden, CE. Cannabis and Psychosis in Teens: Teens have access to extremely potent cannabis. Parents need to understand the risks. Sci Am. 2025;332 (5):90. doi: 10.1038/scientificamerican052025-6xqMsjiHh6k7H816RklzoC. PubMed PMID:40232981 .
- Krystal, JH, Carter, CS, Bearden, CE, Barch, DM, Editors and Editorial Boards of Biological Psychiatry, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, and Biological Psychiatry: Global Open Science, Editorial Committee of the Biological Psychiatry family of journals et al.. Biological Psychiatry: Preserving the Promise. Biol Psychiatry. 2025; :. doi: 10.1016/j.biopsych.2025.03.023. PubMed PMID:40216051 .
- Asgari-Targhi, A, Yao, B, Brown, L, Garcia, S, Nagendra, A, Chin, K et al.. Bridging Science and Hope: integrating and Communicating Lived experience in Accelerating Medicines Partnership® Schizophrenia Program. Schizophrenia (Heidelb). 2025;11 (1):57. doi: 10.1038/s41537-025-00572-7. PubMed PMID:40195300 PubMed Central PMC11977264.
- Billah, T, Cho, KIK, Borders, O, Chung, Y, Ennis, M, Jacobs, GR et al.. Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program. Schizophrenia (Heidelb). 2025;11 (1):55. doi: 10.1038/s41537-025-00560-x. PubMed PMID:40180978 PubMed Central PMC11968805.