Research
Neurogenetic disorders; neurobehavioral biomarkers of serious mental illness
Appointments
- Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior Brain Research Institute
- Integrative Center for Neurobehavioral Genetics
- Center for Autism Research and Treatment (CART)
- Director, Center for the Assessment and Prevention of Prodromal States (CAPPS)
Biography
Her research aims to understand genetic and neurobiological risk factors for the development of early-onset neuropsychiatric disorders. Dr. Bearden’s work examines these questions through two complementary lines of research:
1) The investigation of early biomarkers that predict disease risk and trajectory in at-risk populations; and
2) Translational approaches to understanding disrupted brain circuitry in highly penetrant genetic subtypes (e.g, 22q11.2 microdeletions)
Publications
- Gur, RC, Bearden, CE, Jacquemont, S, Swillen, A, van Amelsvoort, T, van den Bree, M et al.. Neurocognitive profiles of 22q11.2 and 16p11.2 deletions and duplications. Mol Psychiatry. 2024; :. doi: 10.1038/s41380-024-02661-y. PubMed PMID:39048645 .
- Ward, HB, Beermann, A, Xie, J, Yildiz, G, Felix, KM, Addington, J et al.. Robust Brain Correlates of Cognitive Performance in Psychosis and its Prodrome. Biol Psychiatry. 2024; :. doi: 10.1016/j.biopsych.2024.07.012. PubMed PMID:39032726 .
- Chintoh, A, Liu, L, Braun, A, Akseer, S, Bearden, CE, Cadenhead, KS et al.. Sex differences in clinical presentation in youth at high risk for psychosis who transition to psychosis. Schizophr Res. 2024;271 :153-160. doi: 10.1016/j.schres.2024.07.030. PubMed PMID:39029145 .
- Carrión, RE, Ku, BS, Dorvil, S, Auther, AM, McLaughlin, D, Addington, J et al.. Neurocognition in adolescents and young adults at clinical high risk for psychosis: Predictive stability for social and role functioning. Schizophr Res. 2024;271 :129-137. doi: 10.1016/j.schres.2024.06.054. PubMed PMID:39024961 .
- Wang, HR, Liu, ZQ, Nakua, H, Hegarty, CE, Thies, MB, Patel, PK et al.. Decoding Early Psychoses: Unraveling Stable Microstructural Features Associated with Psychopathology Across Independent Cohorts. Biol Psychiatry. 2024; :. doi: 10.1016/j.biopsych.2024.06.011. PubMed PMID:38908657 .