Research
Neurogenetic disorders; neurobehavioral biomarkers of serious mental illness
Appointments
- Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior Brain Research Institute
- Integrative Center for Neurobehavioral Genetics
- Center for Autism Research and Treatment (CART)
- Director, Center for the Assessment and Prevention of Prodromal States (CAPPS)
Biography
Her research aims to understand genetic and neurobiological risk factors for the development of early-onset neuropsychiatric disorders. Dr. Bearden’s work examines these questions through two complementary lines of research:
1) The investigation of early biomarkers that predict disease risk and trajectory in at-risk populations; and
2) Translational approaches to understanding disrupted brain circuitry in highly penetrant genetic subtypes (e.g, 22q11.2 microdeletions)
Publications
- Jeffries, CD, Bizon, CA, Ford, JR, Addington, J, Bearden, CE, Cadenhead, K et al.. Correlation networks of blood proteins in the neuroimmunology of schizophrenia-replication and extension. Transl Psychiatry. 2026; :. doi: 10.1038/s41398-026-03934-6. PubMed PMID:41965717 .
- Ku, BS, Arrant, EJ, Yuan, QE, Aberizk, KM, Addington, JM, Bearden, CE et al.. Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability. Schizophr Res. 2026;293 :81-90. doi: 10.1016/j.schres.2026.03.024. PubMed PMID:41955767 .
- Bai, Y, Vandekar, S, Feola, B, Addington, J, Bearden, CE, Cadenhead, K et al.. Longitudinal Relationships Between Cannabis and Tobacco Use and Symptom Severity in Individuals at Clinical High Risk for Psychosis. medRxiv. 2026; :. doi: 10.64898/2026.03.16.26347411. PubMed PMID:41929302 PubMed Central PMC13042115.
- Peck, FC, Walsh, CR, Truong, H, Pochon, JF, Enriquez, KD, Bearden, CE et al.. Spectral and non-spectral EEG measures in the prediction of working memory task performance and psychopathology. bioRxiv. 2026; :. doi: 10.64898/2026.03.25.714248. PubMed PMID:41929093 PubMed Central PMC13042055.
- Ku, BS, Arrant, EJ, Addington, J, Bearden, CE, Cadenhead, KS, Cannon, TD et al.. Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons. Brain Environ. 2026;5 :. doi: 10.1016/j.braen.2026.100016. PubMed PMID:41907310 PubMed Central PMC13030900.