Research
Neurogenetic disorders; neurobehavioral biomarkers of serious mental illness
Appointments
- Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior Brain Research Institute
- Integrative Center for Neurobehavioral Genetics
- Center for Autism Research and Treatment (CART)
- Director, Center for the Assessment and Prevention of Prodromal States (CAPPS)
Biography
Her research aims to understand genetic and neurobiological risk factors for the development of early-onset neuropsychiatric disorders. Dr. Bearden’s work examines these questions through two complementary lines of research:
1) The investigation of early biomarkers that predict disease risk and trajectory in at-risk populations; and
2) Translational approaches to understanding disrupted brain circuitry in highly penetrant genetic subtypes (e.g, 22q11.2 microdeletions)
Publications
- Calderon, V, Gamarra, JM, Ruiz-Yu, B, Denenny, DM, Zinberg, JL, Bearden, CE et al.. Navigating the Maze: Caregiver Perspectives on Pathways to Mental Health Care for U.S. Youth at Clinical High Risk for Psychosis. Early Interv Psychiatry. 2025;19 (3):e70025. doi: 10.1111/eip.70025. PubMed PMID:40050513 .
- Mourgues-Codern, C, Benrimoh, D, Gandhi, J, Farina, EA, Vin, R, Zamorano, T et al.. Emergence and dynamics of delusions and hallucinations across stages in early psychosis. Biol Psychiatry. 2025; :. doi: 10.1016/j.biopsych.2025.02.891. PubMed PMID:40020853 .
- Calderon, V, Vasquez, ML, Uribe, C, Bearden, CE, Lopez, SR. Navigating Adversity: Ethnoracial Discrimination, Family Support, and Psychotic Symptom Severity in US Latinx People with First Episode Psychosis. J Racial Ethn Health Disparities. 2025; :. doi: 10.1007/s40615-025-02308-w. PubMed PMID:40016590 .
- Liao, Z, Kumar, K, Kopal, J, Huguet, G, Saci, Z, Jean-Louis, M et al.. Copy number variants and the tangential expansion of the cerebral cortex. Nat Commun. 2025;16 (1):1697. doi: 10.1038/s41467-025-56855-1. PubMed PMID:39962045 PubMed Central PMC11833094.
- Bronstein, MV, Kummerfeld, E, Bearden, CE, Cornblatt, BA, Walker, EF, Woods, SW et al.. Delineating empirically plausible causal pathways to suicidality among people at clinical high risk for psychosis. J Psychopathol Clin Sci. 2025; :. doi: 10.1037/abn0000969. PubMed PMID:39913476 .