Research
Neurogenetic disorders; neurobehavioral biomarkers of serious mental illness
Appointments
- Professor, Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior Brain Research Institute
- Integrative Center for Neurobehavioral Genetics
- Center for Autism Research and Treatment (CART)
- Director, Center for the Assessment and Prevention of Prodromal States (CAPPS)
Biography
Her research aims to understand genetic and neurobiological risk factors for the development of early-onset neuropsychiatric disorders. Dr. Bearden’s work examines these questions through two complementary lines of research:
1) The investigation of early biomarkers that predict disease risk and trajectory in at-risk populations; and
2) Translational approaches to understanding disrupted brain circuitry in highly penetrant genetic subtypes (e.g, 22q11.2 microdeletions)
Publications
- Thames, AD, Bearden, CE, Keefe, RSE. In memoriam - Robert M. Bilder, Ph.D. Neuropsychopharmacology. 2026; :. doi: 10.1038/s41386-025-02309-7. PubMed PMID:41520020 .
- Latrèche, C, Mancini, V, Dvojakovska, M, Kushan, L, Mchangama, F, Tairi, F et al.. Multicenter retrospective study on effectiveness, reported side effects, and cognitive outcomes of SSRIs in 22q11.2 deletion syndrome. Res Sq. 2025; :. doi: 10.21203/rs.3.rs-8286229/v1. PubMed PMID:41510244 PubMed Central PMC12776512.
- Hughes, DE, Zapetis, SL, Mordy, A, Lopez, D, Calderon, V, Adery, L et al.. Association between bullying, state-level policy and mental health symptoms in gender diverse youth. medRxiv. 2025; :. doi: 10.64898/2025.12.19.25342709. PubMed PMID:41480027 PubMed Central PMC12755275.
- Jung, B, Schmitt, JE, Seidlitz, J, Schabdach, J, Karandikar, S, Crowley, TB et al.. Leveraging Clinical Neuroimaging to Chart Brain Structure in 22q11.2 Deletion Syndrome. medRxiv. 2025; :. doi: 10.1101/2025.11.25.25339898. PubMed PMID:41358290 PubMed Central PMC12676546.
- Villalón-Reina, JE, Zhu, AH, Benavidez, S, Moreau, CA, Feng, Y, Chattopadhyay, T et al.. Lifespan Normative Modeling of Brain Microstructure. bioRxiv. 2025; :. doi: 10.1101/2024.12.15.628527. PubMed PMID:41256711 PubMed Central PMC12621655.