Research
Functional magnetic resonance imaging, language, memory
Appointments
- Clinical Neuropsychologist, Resnick Neuropsychiatric Hospital
- Professor, Psychiatry and Biobehavioral Sciences
- Center for Autism Research and Treatment (CART)
- Staglin Center for Cognitive Neuroscience
- Professor in Residence, Cognitive Psychology
- Tennenbaum Center for the Biology of Creativity
- Member, Brain Research Institute
- Neuroengineering Training Program
- Neuroscience GPB Home Area
Biography
Dr. Bookheimer’s research examines the neuroanatomy of higher cognitive functions- specifically, understanding how memory and language functions are organized in the human brain in health and disease.
The laboratory focuses on functional neuroimaging techniques (functional magnetic resonance imaging, Positron Emission Tomography, and optical intrinsic signal imaging), in combination with invasive techniques (electrocorticography and intracarotid amobarbitol (Wada) testing ) to develop an integrated knowledge of language and memory representations in normal humans and those with neurological and psychiatric disorders affecting language and memory.
A large focus of research activity involves developing this new technology into tools that can benefit patients with developmental and neurological disorders.
Publications
- Arutiunian, V, Santhosh, M, Neuhaus, E, Sullivan, CAW, Bernier, RA, Bookheimer, SY et al.. A common genetic variant in the Neurexin family member CNTNAP2 is related to language but not communication skills in youth with Autism Spectrum Disorder. Autism Res. 2024; :. doi: 10.1002/aur.3193. PubMed PMID:38984666 .
- Than, A, Patterson, G, Cummings, KK, Jung, J, Cakar, ME, Abbas, L et al.. Sensory over-responsivity and atypical neural responses to socially relevant stimuli in autism. Autism Res. 2024;17 (7):1328-1343. doi: 10.1002/aur.3179. PubMed PMID:38949436 PubMed Central PMC11272439.
- Bookheimer, TH, Ganapathi, AS, Iqbal, F, Popa, ES, Mattinson, J, Bramen, JE et al.. Beyond the hippocampus: Amygdala and memory functioning in older adults. Behav Brain Res. 2024;471 :115112. doi: 10.1016/j.bbr.2024.115112. PubMed PMID:38871129 .
- Arutiunian, V, Santhosh, M, Neuhaus, E, Borland, H, Tompkins, C, Bernier, RA et al.. The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives. Mol Autism. 2024;15 (1):19. doi: 10.1186/s13229-024-00598-1. PubMed PMID:38711098 PubMed Central PMC11075235.
- Tsang, T, Green, SA, Liu, J, Lawrence, K, Jeste, S, Bookheimer, SY et al.. Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism. Commun Biol. 2024;7 (1):485. doi: 10.1038/s42003-024-06016-9. PubMed PMID:38649483 PubMed Central PMC11035613.