Intellectual and Developmental Disabilities Research Center

FACULTY

Bookheimer, Susan, Ph.D.

Research

Functional magnetic resonance imaging, language, memory

Appointments

  • Clinical Neuropsychologist, Resnick Neuropsychiatric Hospital
  • Professor, Psychiatry and Biobehavioral Sciences
  • Center for Autism Research and Treatment (CART)
  • Staglin Center for Cognitive Neuroscience
  • Professor in Residence, Cognitive Psychology
  • Tennenbaum Center for the Biology of Creativity
  • Member, Brain Research Institute
  • Neuroengineering Training Program
  • Neuroscience GPB Home Area

Biography

Dr. Bookheimer’s research examines the neuroanatomy of higher cognitive functions- specifically, understanding how memory and language functions are organized in the human brain in health and disease.

The laboratory focuses on functional neuroimaging techniques (functional magnetic resonance imaging, Positron Emission Tomography, and optical intrinsic signal imaging), in combination with invasive techniques (electrocorticography and intracarotid amobarbitol (Wada) testing ) to develop an integrated knowledge of language and memory representations in normal humans and those with neurological and psychiatric disorders affecting language and memory.

A large focus of research activity involves developing this new technology into tools that can benefit patients with developmental and neurological disorders.

Publications

  1. Arutiunian, V, Santhosh, M, Neuhaus, E, Borland, H, Tompkins, C, Bernier, RA et al.. The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives. Mol Autism. 2024;15 (1):19. doi: 10.1186/s13229-024-00598-1. PubMed PMID:38711098 PubMed Central PMC11075235.
  2. Tsang, T, Green, SA, Liu, J, Lawrence, K, Jeste, S, Bookheimer, SY et al.. Salience network connectivity is altered in 6-week-old infants at heightened likelihood for developing autism. Commun Biol. 2024;7 (1):485. doi: 10.1038/s42003-024-06016-9. PubMed PMID:38649483 PubMed Central PMC11035613.
  3. Cakar, ME, Okada, NJ, Cummings, KK, Jung, J, Bookheimer, SY, Dapretto, M et al.. Functional connectivity of the sensorimotor cerebellum in autism: associations with sensory over-responsivity. Front Psychiatry. 2024;15 :1337921. doi: 10.3389/fpsyt.2024.1337921. PubMed PMID:38590791 PubMed Central PMC10999625.
  4. Cichocki, AC, Zinbarg, RE, Craske, MG, Chat, IK, Young, KS, Bookheimer, SY et al.. Transdiagnostic symptom of depression and anxiety associated with reduced gray matter volume in prefrontal cortex. Psychiatry Res Neuroimaging. 2024;339 :111791. doi: 10.1016/j.pscychresns.2024.111791. PubMed PMID:38359709 PubMed Central PMC10938645.
  5. Miller, GE, Carroll, AL, Armstrong, CC, Craske, MG, Zinbarg, RE, Bookheimer, SY et al.. Major stress in early childhood strengthens the association between peripheral inflammatory activity and corticostriatal responsivity to reward. Brain Behav Immun. 2024;117 :215-223. doi: 10.1016/j.bbi.2024.01.013. PubMed PMID:38244947 PubMed Central PMC10932835.
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