Intellectual and Developmental Disabilities Research Center


Colwell, Christopher, Ph.D.


Circadian rhythms, neural control of behavior


  • Professor, Psychiatry and Biobehavioral Sciences
  • Member, ACCESS Program: Dept. of Molecular, Cell & Integrative Physiology
  • Neuroscience IDP
  • Brain Research Institute
  • Faculty, Molecular, Cellular, and Integrative Physiology IDP


The Colwell laboratory’s research has focused on understanding the mechanisms underlying circadian rhythms in mammals. Dysfunction in the timing of these daily cycles is a key symptom in a number of neurological and psychiatric disorders.

Better understanding of the basic biology of this timing system should result in new therapies to improve the quality of life of these patients and the people who care for them.


  1. Oster, H, Colwell, CS. Editorial: Recent advances in sleep and circadian rhythms: the hypothalamus and its relationship with appetite. Front Neurosci. 2024;18 :1385619. doi: 10.3389/fnins.2024.1385619. PubMed PMID:38486970 PubMed Central PMC10937535.
  2. Swisher, V, Tooker, M, Qu, C, Burgess, HJ, Coles, ME, Bennett, S et al.. Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders. Child Health Care. 2024;53 (1):23-40. doi: 10.1080/02739615.2023.2175682. PubMed PMID:38435344 PubMed Central PMC10904019.
  3. Chiem, E, Zhao, K, Stark, G, Ghiani, CA, Colwell, CS, Paul, KN et al.. Sex differences in sleep architecture in a mouse model of Huntington's disease. J Neurosci Res. 2024;102 (1):e25290. doi: 10.1002/jnr.25290. PubMed PMID:38284849 .
  4. Vincent, SM, Madani, M, Dikeman, D, Golden, K, Crocker, N, Jackson, C et al.. Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice. Sleep Adv. 2024;5 (1):zpad057. doi: 10.1093/sleepadvances/zpad057. PubMed PMID:38264142 PubMed Central PMC10803172.
  5. Marin, MA, Gleichman, AJ, Wei, X, Whittaker, DS, Mody, I, Colwell, CS et al.. Motor Activity-Induced White Matter Repair in White Matter Stroke. J Neurosci. 2023;43 (48):8126-8139. doi: 10.1523/JNEUROSCI.0631-23.2023. PubMed PMID:37821228 PubMed Central PMC10697402.
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