Intellectual and Developmental Disabilities Research Center

FACULTY

Colwell, Christopher, Ph.D.

Research

Circadian rhythms, neural control of behavior

Appointments

  • Professor, Psychiatry and Biobehavioral Sciences
  • Member, ACCESS Program: Dept. of Molecular, Cell & Integrative Physiology
  • Neuroscience IDP
  • Brain Research Institute
  • Faculty, Molecular, Cellular, and Integrative Physiology IDP

Appointments

The Colwell laboratory’s research has focused on understanding the mechanisms underlying circadian rhythms in mammals. Dysfunction in the timing of these daily cycles is a key symptom in a number of neurological and psychiatric disorders.

Better understanding of the basic biology of this timing system should result in new therapies to improve the quality of life of these patients and the people who care for them.

Publications

  1. Saravanapandian, V, Madani, M, Nichols, I, Vincent, S, Dover, M, Dikeman, D et al.. Sleep EEG signatures in mouse models of 15q11.2-13.1 duplication (Dup15q) syndrome. J Neurodev Disord. 2024;16 (1):39. doi: 10.1186/s11689-024-09556-7. PubMed PMID:39014349 PubMed Central PMC11251350.
  2. Longcore, T, Villanueva, SAMB, Nguyen-Ngo, K, Ghiani, CA, Harrison, B, Colwell, CS et al.. Relative importance of intensity and spectrum of artificial light at night in disrupting behavior of a nocturnal rodent. J Exp Biol. 2024;227 (14):. doi: 10.1242/jeb.247235. PubMed PMID:38873751 .
  3. Chiem, E, Zhao, K, Dell'Angelica, D, Ghiani, CA, Paul, KN, Colwell, CS et al.. Scheduled feeding improves sleep in a mouse model of Huntington's disease. bioRxiv. 2024; :. doi: 10.1101/2024.05.04.592428. PubMed PMID:38766112 PubMed Central PMC11100594.
  4. Oster, H, Colwell, CS. Editorial: Recent advances in sleep and circadian rhythms: the hypothalamus and its relationship with appetite. Front Neurosci. 2024;18 :1385619. doi: 10.3389/fnins.2024.1385619. PubMed PMID:38486970 PubMed Central PMC10937535.
  5. Swisher, V, Tooker, M, Qu, C, Burgess, HJ, Coles, ME, Bennett, S et al.. Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders. Child Health Care. 2024;53 (1):23-40. doi: 10.1080/02739615.2023.2175682. PubMed PMID:38435344 PubMed Central PMC10904019.
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