Research
Hypoxic-ischemic brain injury; Fetal origins of adult disease
Appointments
- Department of Pediatrics
Biography
Devaskar’s laboratory is focused on determining the role of glucose transporters in mediating neuronal function. This is being pursued by the generation of various transgenic and knock out mouse models and phenotypic characterization.
The second area is around delineating the role of hypothalamic leptin resistance during development in the future development of obesity, providing mechanisms towards the theory of “fetal origins of adult disease”. Various signal transduction pathways are being examined and dysregulation of these pathways contributing towards the subsequent development of obesity are being explored.
Publications
- Ghosh, S, Ganguly, A, Habib, M, Shin, BC, Thamotharan, S, Andersson, S et al.. Hepatic and Pancreatic Cellular Response to Early Life Nutritional Mismatch. Endocrinology. 2025; :. doi: 10.1210/endocr/bqaf007. PubMed PMID:39823439 .
- Fortes, PA, Janzen, C, Lei, MYY, Vangala, S, Sung, K, Devaskar, SU et al.. Does Amsterdam criteria applied to largely unsubmitted term placentas with favorable fetal outcomes show significant maternal clinicopathologic correlation?. Am J Clin Pathol. 2025; :. doi: 10.1093/ajcp/aqae174. PubMed PMID:39761233 .
- Dammann, CE, Alvira, CM, Devaskar, SU, St Geme, JW 3rd, Golden, WC, Gordon, CM et al.. Pediatric subspecialty workforce: what is needed to secure its vitality and survival?. Pediatr Res. 2024; :. doi: 10.1038/s41390-024-03607-4. PubMed PMID:39455858 .
- Meng, Q, Mitra, S, Del Rosario, I, Jerrett, M, Janzen, C, Devaskar, SU et al.. Urinary polycyclic aromatic hydrocarbon metabolites and their association with oxidative stress among pregnant women in Los Angeles. Environ Health. 2024;23 (1):68. doi: 10.1186/s12940-024-01107-w. PubMed PMID:39138494 PubMed Central PMC11321171.
- Ganguly, A, Ghosh, S, Jin, P, Wadehra, M, Devaskar, SU. Omega-3 reverses the metabolic and epigenetically regulated placental phenotype acquired from preconceptional and peri-conceptional exposure to air pollutants. J Nutr Biochem. 2024;134 :109735. doi: 10.1016/j.jnutbio.2024.109735. PubMed PMID:39122219 .