Members

Devaskar, Sherin, Ph.D.

Research

Hypoxic-ischemic brain injury; Fetal origins of adult disease

Appointments

  • Department of Pediatrics

Biography

Devaskar’s laboratory is focused on determining the role of glucose transporters in mediating neuronal function. This is being pursued by the generation of various transgenic and knock out mouse models and phenotypic characterization.

The second area is around delineating the role of hypothalamic leptin resistance during development in the future development of obesity, providing mechanisms towards the theory of “fetal origins of adult disease”. Various signal transduction pathways are being examined and dysregulation of these pathways contributing towards the subsequent development of obesity are being explored.

Publications

  1. Ramirez, RO, Kim, JJ, Fortes, PA, Janzen, C, Sullivan, P, Devaskar, SU et al.. Association between MRI-derived early second trimester placental physiology and birth weight percentiles in pregnancies without ischemic placenta disease (IPD). Placenta. 2025;172 :120-130. doi: 10.1016/j.placenta.2025.11.003. PubMed PMID:41223521 .
  2. Presicce, P, Morselli, M, Jeong, A, Altendahl, M, Martinez, G, Del Vecchio, G et al.. Placental Privilege: Evidence of organ resilience in severe COVID-19 in pregnancy. Placenta. 2025; :. doi: 10.1016/j.placenta.2025.05.003. PubMed PMID:40383676 .
  3. Garg, M, Devaskar, SU. Exploring the long-term impacts of neonatal hypoglycemia to determine a safe threshold for glucose concentrations. Eur J Pediatr. 2025;184 (4):263. doi: 10.1007/s00431-025-06082-z. PubMed PMID:40119223 PubMed Central PMC11928350.
  4. Yu, KE, Mitra, S, Meng, Q, DelRosario, I, Devaskar, SU, Janzen, C et al.. Diet, polycyclic aromatic hydrocarbons, and oxidative stress biomarkers in pregnancy: A Los Angeles pregnancy cohort. Environ Res. 2025;275 :121399. doi: 10.1016/j.envres.2025.121399. PubMed PMID:40088999 .
  5. Ghosh, S, Ganguly, A, Habib, M, Shin, BC, Thamotharan, S, Andersson, S et al.. Hepatic and Pancreatic Cellular Response to Early Life Nutritional Mismatch. Endocrinology. 2025;166 (3):. doi: 10.1210/endocr/bqaf007. PubMed PMID:39823439 PubMed Central PMC11815087.
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