Research
Hypoxic-ischemic brain injury; Fetal origins of adult disease
Appointments
- Department of Pediatrics
Biography
Devaskar’s laboratory is focused on determining the role of glucose transporters in mediating neuronal function. This is being pursued by the generation of various transgenic and knock out mouse models and phenotypic characterization.
The second area is around delineating the role of hypothalamic leptin resistance during development in the future development of obesity, providing mechanisms towards the theory of “fetal origins of adult disease”. Various signal transduction pathways are being examined and dysregulation of these pathways contributing towards the subsequent development of obesity are being explored.
Publications
- Lakshminrusimha, S, Li, ST, DeLemos, CD, Moss, CR, Hoffman, J, Johnstone, L et al.. Anticipating the Effects of ACGME-mandated Residency Curriculum Changes on NICU Staffing Models and Costs. J Pediatr. 2024; :114210. doi: 10.1016/j.jpeds.2024.114210. PubMed PMID:39053882 .
- Ghosh, S, Thamotharan, S, Fong, J, Lei, MYY, Janzen, C, Devaskar, SU et al.. Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia. Sci Rep. 2024;14 (1):16770. doi: 10.1038/s41598-024-64057-w. PubMed PMID:39039088 PubMed Central PMC11263608.
- Ganguly, A, Ghosh, S, Shin, BC, Touma, M, Wadehra, M, Devaskar, SU et al.. Gestational exposure to air pollutants perturbs metabolic and placenta-fetal phenotype. Reprod Toxicol. 2024;128 :108657. doi: 10.1016/j.reprotox.2024.108657. PubMed PMID:39002939 .
- Meng, Q, Liu, J, Shen, J, Del Rosario, I, Janzen, C, Devaskar, SU et al.. Ambient exposure to fine particulate matter with oxidative potential affects oxidative stress biomarkers in pregnancy. Am J Epidemiol. 2024; :. doi: 10.1093/aje/kwae152. PubMed PMID:38918040 .
- Lakshminrusimha, S, Lubarsky, DA, Gamber, RA, Devaskar, SU. The National Academies of Sciences, Engineering, and Medicine recommendations on Medicaid parity and future of pediatric subspecialty workforce. J Perinatol. 2024; :. doi: 10.1038/s41372-024-01961-z. PubMed PMID:38594412 .