Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Wang, C, Zhao, X, Jiang, J, Jia, M, Shi, W, Wu, Z et al.. Integrated chemical analysis, metabolic profiling, network pharmacology, molecular docking and toxicity prediction to reveal the active ingredients and their safety of raw and prepared rhubarbs in the treatment of gastric ulcers. Front Pharmacol. 2024;15 :1481091. doi: 10.3389/fphar.2024.1481091. PubMed PMID:39624840 PubMed Central PMC11608977.
- Ni, R, Ji, XY, Cao, T, Liu, XW, Wang, C, Lu, C et al.. Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction. Acta Pharmacol Sin. 2024; :. doi: 10.1038/s41401-024-01424-3. PubMed PMID:39623043 .
- Zhu, L, Zhang, Y, Ding, J, Xin, W, Fan, GC, Song, ZL et al.. Intelligent DNA Nanosystem for Broad-Spectrum Oncological Typing and Therapy. ACS Sens. 2024; :. doi: 10.1021/acssensors.4c02246. PubMed PMID:39622787 .
- Liu, Q, Fan, G, Bi, J, Fang, Q, Luo, F, Huang, X et al.. Exposure to multiple metals and leukocyte telomere length in children and adolescents: The mediating effect of thyroid hormones. Environ Res. 2024;265 :120483. doi: 10.1016/j.envres.2024.120483. PubMed PMID:39613012 .
- Wei, D, Yu, B, Chen, D, Fan, G, Yan, W, Cui, W et al.. Micro-Nanofiber Three-Dimensional Antibacterial Sponge with Wetting/Pore Dual Gradient for Rapid Liquid Infiltration and Uniform Retention in Diapers. ACS Appl Mater Interfaces. 2024; :. doi: 10.1021/acsami.4c15094. PubMed PMID:39611352 .