Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Sun, S, Ma, G, Cheng, L, Zhang, H, Fan, G, Wu, L et al.. Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1. Br J Cancer. 2026; :. doi: 10.1038/s41416-026-03395-0. PubMed PMID:41957137 .
- Rapushi, E, Aryal, A, Yang, T, Li, Z, Wang, X, Fan, GC et al.. Mitochondria-Derived Vesicles and Mitochondrial Extracellular Vesicles in Health and Cardiovascular Disease. Circ Res. 2026;138 (8):e327357. doi: 10.1161/CIRCRESAHA.125.327357. PubMed PMID:41955324 .
- Song, Z, Wang, C, Xie, Z, Liu, C, Zhou, Q, Ye, M et al.. Construction of oxygen-bridged multi-interface sites in nanotubes for high-efficiency electrocatalytic nitrite reduction to ammonia. Chem Commun (Camb). 2026; :. doi: 10.1039/d6cc00174b. PubMed PMID:41947715 .
- Chen, L, Jiang, L, Han, X, Zhang, R, Zhao, F, Fan, G et al.. The effectiveness and potential regulatory mechanism of Blumea balsamifera derived extracellular vesicles in promoting burn wound healing. Front Cell Dev Biol. 2026;14 :1756718. doi: 10.3389/fcell.2026.1756718. PubMed PMID:41938535 PubMed Central PMC13044083.
- Zhao, Y, Xia, JH, Wang, R, Ma, XQ, Fan, GW, Liu, ST et al.. Development and validation of a risk prediction model for frailty in middle-aged and old adults with cardiovascular metabolic multimorbidity. Geriatr Nurs. 2026;70 :104039. doi: 10.1016/j.gerinurse.2026.104039. PubMed PMID:41936337 .