Fan, Guoping, Ph.D.

Research

Molecular and cellular mechanisms underlying neural development

Appointments

• Professor, Human Genetics
• Member, Bioinformatics GPB Home Area
• Brain Research Institute
• Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
• Gene Regulation GPB Home Area
• Genetics & Genomics GPB Home Area
• JCCC Gene Regulation Program Area
• Neuroscience GPB Home Area

Appointments

His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.

Publications

1. Wang, J, Wang, X, Song, Y, Huang, Z, Wu, H, Chang, L et al.. Huopuxialing Decoction: A Promising Candidate for Precancerous Lesions of Gastric Cancer Treatment Based on Bioinformatics and Experimental Verification. Comb Chem High Throughput Screen. 2024; :. doi: 10.2174/0113862073325718240827073225. PubMed PMID:39289939 .
2. Chen, D, Fan, G, Xu, Y, Luo, P, Chen, Q, Chen, X et al.. A novel homozygous mutation in the DNAAF3 gene leads to severe asthenozoospermia and teratospermia. J Cell Mol Med. 2024;28 (18):e70092. doi: 10.1111/jcmm.70092. PubMed PMID:39289782 .
3. Cao, Z, Wang, X, Zeng, Z, Yang, Z, Lin, Y, Sun, L et al.. The improvement of modified Si-Miao granule on hepatic insulin resistance and glycogen synthesis in type 2 diabetes mellitus involves the inhibition of TNF-α/JNK1/IRS-2 pathway: network pharmacology, molecular docking, and experimental validation. Chin Med. 2024;19 (1):128. doi: 10.1186/s13020-024-00997-9. PubMed PMID:39285464 .
4. Ma, J, Basit, RA, Yuan, S, Zhao, X, Liu, X, Fan, G et al.. Optimization of fermentation conditions for the production of recombinant feruloyl esterase BpFae^T132C-D143C. Folia Microbiol (Praha). 2024; :. doi: 10.1007/s12223-024-01197-6. PubMed PMID:39283535 .
5. Pu, Q, Qian, J, Zhang, Y, Yang, S, Huang, H, Chao, Q et al.. The Influence of Post-Treatment on Micropore Evolution and Mechanical Performance in AlSi10Mg Alloy Manufactured by Laser Powder Bed Fusion. Materials (Basel). 2024;17 (17):. doi: 10.3390/ma17174319. PubMed PMID:39274709 PubMed Central PMC11396521.

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