Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Chen, P, Fan, G, Shen, H, Xiao, Q, Yang, J, Jiang, L et al.. The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit. J Vis Exp. 2025; (226):. doi: 10.3791/68554. PubMed PMID:41460766 .
- Zhang, P, Liu, Y, Yang, H, Li, J, Fan, G, Bai, H et al.. Inhibition of GDF15/GFRAL: A novel opportunity for the treatment of solid tumors. Int Immunopharmacol. 2025;170 :116109. doi: 10.1016/j.intimp.2025.116109. PubMed PMID:41455368 .
- Fan, G, Guo, W, Lu, J, He, Y, Zha, J, Zhang, Q et al.. CADD-engineered peptide protacs efficiently target PCSK9 for hypercholesterolemia in vivo. Metabolism. 2025; :156485. doi: 10.1016/j.metabol.2025.156485. PubMed PMID:41448485 .
- Zhang, J, Geng, S, Fan, G, Ma, J. Editorial: Innovative approaches for wound treatment. Front Pharmacol. 2025;16 :1738213. doi: 10.3389/fphar.2025.1738213. PubMed PMID:41446783 PubMed Central PMC12722801.
- Li, X, Lin, R, Wen, P, Li, L, Xie, L, Lu, Y et al.. A qualitative study on the current status and needs of unintentional injury prevention and control interventions for children aged 3-12 in Guizhou Province, China. Front Public Health. 2025;13 :1712091. doi: 10.3389/fpubh.2025.1712091. PubMed PMID:41446533 PubMed Central PMC12722910.