Fan, Guoping, Ph.D.

Research

Molecular and cellular mechanisms underlying neural development

Appointments

• Professor, Human Genetics
• Member, Bioinformatics GPB Home Area
• Brain Research Institute
• Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
• Gene Regulation GPB Home Area
• Genetics & Genomics GPB Home Area
• JCCC Gene Regulation Program Area
• Neuroscience GPB Home Area

Appointments

His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.

Publications

1. Guo, P, He, W, Geng, J, Fan, G, Tian, H, Zhan, P et al.. Dual protective function of L-arginine on color and flavor quality of kiwifruit juice during thermal processing. Food Chem. 2025;501 :147562. doi: 10.1016/j.foodchem.2025.147562. PubMed PMID:41418545 .
2. Yang, F, Fan, G, Cao, J, Zhao, Q, Guo, K, Liu, M et al.. Cancer-specific bivalent promoters featuring low-level H3K27me3 signals favor active transcription and govern the cancer cell state transition. Acta Biochim Biophys Sin (Shanghai). 2025; :. doi: 10.3724/abbs.2025234. PubMed PMID:41414814 .
3. Du, W, Ringer, M, Huang, W, Desai, D, Khandakar, GI, Tron Esqueda, L et al.. Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction. Circulation. 2025; :. doi: 10.1161/CIRCULATIONAHA.124.071774. PubMed PMID:41410033 .
4. Fan, G, Zhang, K, Yang, X, Ding, J, Wang, Z, Li, J et al.. Correction: Prognostic value of circulating tumor DNA in patients with colon cancer: Systematic review. PLoS One. 2025;20 (12):e0338537. doi: 10.1371/journal.pone.0338537. PubMed PMID:41396853 PubMed Central PMC12704840.
5. Zhou, P, Wu, Q, Fan, G, Yang, Z, Bao, S, Li, J et al.. The ameliorative effects of fermented Chinese herbal medicine on growth inhibition and liver damage induced by manganese exposure in largemouth bass (Micropterus salmoides). Fish Physiol Biochem. 2025;51 (6):206. doi: 10.1007/s10695-025-01619-3. PubMed PMID:41396323 .

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