Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Liu, Z, Qu, H, Li, Z, Wang, S, Wu, Z, Zhao, X et al.. Sex and age disparities in goserelin safety: a global pharmacovigilance study. Naunyn Schmiedebergs Arch Pharmacol. 2026; :. doi: 10.1007/s00210-026-05178-z. PubMed PMID:41796237 .
- Song, Y, Yuan, Z, Fang, C, Zhang, S, Yang, L, Hu, M et al.. A genomic compendium of hundreds of teleost fishes reveals their evolutionary landscape. Innovation (Camb). 2026;7 (3):101177. doi: 10.1016/j.xinn.2025.101177. PubMed PMID:41789145 PubMed Central PMC12957567.
- Yang, T, Li, Z, Pan, M, Wang, X, Huang, W, Kesten, NE et al.. Identification of MTURN as a trained immunity-related biomarker for heart failure via integrative transcriptomic machine learning analysis and experimental validation. Front Immunol. 2026;17 :1739660. doi: 10.3389/fimmu.2026.1739660. PubMed PMID:41789108 PubMed Central PMC12957145.
- Luo, T, Fan, G, Zhang, S, Fan, Z, Chen, M, Kong, Z et al.. Mechanical degradation induced by the alkaline water effects of weakly cemented fine-grained sandstone. Sci Rep. 2026; :. doi: 10.1038/s41598-025-34061-9. PubMed PMID:41786803 .
- Dang, Q, Peng, L, Niu, Y, Pan, X, Ye, Z, Wang, T et al.. Targeting ACSS2 disrupts metabolic-epigenetic crosstalk to restore apoptosis and temozolomide chemosensitivity in pancreatic neuroendocrine tumors. Cancer Lett. 2026;645 :218406. doi: 10.1016/j.canlet.2026.218406. PubMed PMID:41786280 .