Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Qi, Z, Liu, Q, Li, H, Zhang, Y, Yu, Z, Luo, W et al.. Telomere-to-telomere genome assembly of Electrophorus electricus provides insights into the evolution of electric eels. Gigascience. 2025;14 :. doi: 10.1093/gigascience/giaf024. PubMed PMID:40167991 .
- Wei, L, Ding, E, Lu, D, Rui, Z, Shen, J, Fan, G et al.. Assessing the effect of modifiable risk factors on hepatocellular carcinoma: evidence from a bidirectional Mendelian randomization analysis. Discov Oncol. 2025;16 (1):437. doi: 10.1007/s12672-025-02177-z. PubMed PMID:40164825 PubMed Central PMC11958933.
- He, ZZ, Shao, WW, Honnay, O, Liao, H, Chen, H, Liu, J et al.. Temporal Dynamics of Genetic Diversity in Protected and Unprotected Wild Rice (Oryza rufipogon) Populations: Implications for Conservation. Mol Ecol. 2025; :e17750. doi: 10.1111/mec.17750. PubMed PMID:40156220 .
- Zhang, Z, Liu, T, Fan, G, Li, N, Li, B, Pu, Y et al.. SpineMamba: Enhancing 3D spinal segmentation in clinical imaging through residual visual Mamba layers and shape priors. Comput Med Imaging Graph. 2025;123 :102531. doi: 10.1016/j.compmedimag.2025.102531. PubMed PMID:40154009 .
- Hu, J, Xu, B, Yan, J, Fan, G. Decarburization, denitrification characteristics and microbial community analysis of a full-scale two-stage anoxic-oxic process for treating refractory coking wastewater. RSC Adv. 2025;15 (12):9398-9407. doi: 10.1039/d5ra00218d. PubMed PMID:40151537 PubMed Central PMC11948310.