Fan, Guoping, Ph.D.

Research

Molecular and cellular mechanisms underlying neural development

Appointments

• Professor, Human Genetics
• Member, Bioinformatics GPB Home Area
• Brain Research Institute
• Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
• Gene Regulation GPB Home Area
• Genetics & Genomics GPB Home Area
• JCCC Gene Regulation Program Area
• Neuroscience GPB Home Area

Appointments

His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.

Publications

1. Xiong, J, Huang, J, Xu, H, Wu, Q, Zhao, J, Chen, Y et al.. CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages. Adv Sci (Weinh). 2025; :e2412881. doi: 10.1002/advs.202412881. PubMed PMID:39985265 .
2. Deng, X, Fan, G. Tuning up gene transcription via direct crosstalk of DNA and RNA methylation. Mol Cell. 2025;85 (4):674-676. doi: 10.1016/j.molcel.2025.01.030. PubMed PMID:39983671 .
3. Zhang, Y, Fan, G, Zheng, L, Li, F. Synergistic Surface-Interface Catalysis in Potassium-Loaded Cu/CoO_x Catalysts to Boost Ethanol Production from CO₂ Hydrogenation. ACS Appl Mater Interfaces. 2025; :. doi: 10.1021/acsami.4c18112. PubMed PMID:39982849 .
4. Wang, L, Zhang, Y, Geng, S, Ma, L, Wang, Y, Han, D et al.. A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy. Front Pharmacol. 2025;16 :1504120. doi: 10.3389/fphar.2025.1504120. PubMed PMID:39981178 PubMed Central PMC11841398.
5. Tao, Y, Xu, F, Han, J, Deng, C, Liang, R, Chen, L et al.. External Validation of the IMPROVE Risk Score for Predicting Bleeding in Hospitalized COVID-19 Patients. J Gen Intern Med. 2025; :. doi: 10.1007/s11606-025-09431-8. PubMed PMID:39979703 .

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