Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Geng, Y, Fan, G, Dong, Z, Yin, P, Meng, Q, Zhao, L et al.. High-Performance Quasi-Solid Thermogalvanic Cells via Crown-Ether-Mediated Ion Migration. ACS Nano. 2025; :. doi: 10.1021/acsnano.5c11865. PubMed PMID:41312679 .
- Jiang, F, Yang, H, Zhai, X, Zhao, Z, Fan, G. Bioactive Flavonoids from Paulownia tomentosa Flowers: Extraction Optimization and α-Glucosidase Inhibitory Kinetics. Foods. 2025;14 (22):. doi: 10.3390/foods14223941. PubMed PMID:41300099 PubMed Central PMC12652004.
- Zhou, N, Fan, G, Yang, N, Xu, T, Zhang, Y, Xu, W et al.. A Cascaded RPA-SDA Amplification Strategy on a Sliding Microfluidic Chip for the Ultrasensitive and Rapid Detection of Shigella. Foods. 2025;14 (22):. doi: 10.3390/foods14223891. PubMed PMID:41300049 PubMed Central PMC12651771.
- Loncke, J, de Ridder, I, La Rovere, R, Vaarmann, A, Fan, G, Ahuja, K et al.. CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons. Acta Neuropathol Commun. 2025;13 (1):242. doi: 10.1186/s40478-025-02132-7. PubMed PMID:41299767 PubMed Central PMC12659354.
- Lin, J, Chen, S, Tan, D, Yang, X, Guo, W, Cang, P et al.. Long-term Senolytic Treatment Prevents Endothelial Dysfunction in Arterial Aging. Aging Dis. 2025; :. doi: 10.14336/AD.2025.0976. PubMed PMID:41296931 .