Research
Molecular and cellular mechanisms underlying neural development
Appointments
- Professor, Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
- Gene Regulation GPB Home Area
- Genetics & Genomics GPB Home Area
- JCCC Gene Regulation Program Area
- Neuroscience GPB Home Area
Appointments
His current research focuses on the actions of DNA methylation and chromatin-remodeling in regulating neural gene expression, neuronal function, and stem cell differentiation and reprogramming.
Publications
- Fan, G, Guo, W, Lu, J, He, Y, Zha, J, Zhang, Q et al.. CADD-engineered peptide protacs efficiently target PCSK9 for hypercholesterolemia in vivo. Metabolism. 2025; :156485. doi: 10.1016/j.metabol.2025.156485. PubMed PMID:41448485 .
- Zhang, J, Geng, S, Fan, G, Ma, J. Editorial: Innovative approaches for wound treatment. Front Pharmacol. 2025;16 :1738213. doi: 10.3389/fphar.2025.1738213. PubMed PMID:41446783 PubMed Central PMC12722801.
- Li, X, Lin, R, Wen, P, Li, L, Xie, L, Lu, Y et al.. A qualitative study on the current status and needs of unintentional injury prevention and control interventions for children aged 3-12 in Guizhou Province, China. Front Public Health. 2025;13 :1712091. doi: 10.3389/fpubh.2025.1712091. PubMed PMID:41446533 PubMed Central PMC12722910.
- Saultz, JN, Bottomly, D, Burns, F, Byrd, K, Kosaka, Y, Alber, B et al.. The aryl hydrocarbon receptor is associated with monocytic AML and innate immune resistance reversible with an AHR inhibitor. Front Immunol. 2025;16 :1554166. doi: 10.3389/fimmu.2025.1554166. PubMed PMID:41445756 PubMed Central PMC12722994.
- Hu, Y, Fan, Z, Dai, Q, Qiao, Y, Niu, B, Ao, Y et al.. Large-scale, high-uniformity evanescent field illumination via a cost-effective polymer-integrated optical waveguide. Opt Lett. 2026;51 (1):41-44. doi: 10.1364/OL.574760. PubMed PMID:41442348 .