Research
Developmental neurogenetics
Appointments
- Director, Center for Autism Research and Treatment (CART)
- Professor, Neurology
- Psychiatry and Biobehavioral Sciences
- Co-Director, Center for Neurobehavioral Genetics
- Professor in Residence, Tennenbaum Center for the Biology of Creativity
- Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- CTSI
- Genetics & Genomics GPB Home Area
- Neuroscience GPB Home Area
- Research Education, Training, and Career Development Program (CTSI-ED)
Appointments
Dr. Geschwind’s laboratory conducts research in three primary areas of neurogenetics:
- autism and language;
- focal neurodegenerative syndromes;
- and the structural/molecular basis of human cognitive specializations.
Utilizing a multi-pronged approach, he studies normal human and animal model brain patterning to diseases in which language and social communication are disrupted, such as autism.
Publications
- Shade, LMP, Katsumata, Y, Abner, EL, Aung, KZ, Claas, SA, Qiao, Q et al.. Publisher Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. Nat Genet. 2025; :. doi: 10.1038/s41588-024-02046-5. PubMed PMID:40527985 .
- Shade, LMP, Katsumata, Y, Abner, EL, Aung, KZ, Claas, SA, Qiao, Q et al.. Author Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. Nat Genet. 2025; :. doi: 10.1038/s41588-024-02045-6. PubMed PMID:40527984 .
- Saloner, R, Staffaroni, AM, Dammer, EB, Johnson, ECB, Paolillo, EW, Wise, A et al.. Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Nat Aging. 2025;5 (6):1143-1158. doi: 10.1038/s43587-025-00878-2. PubMed PMID:40380000 .
- Pottier, C, Küçükali, F, Baker, M, Batzler, A, Jenkins, GD, van Blitterswijk, M et al.. Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing. Nat Commun. 2025;16 (1):3914. doi: 10.1038/s41467-025-59216-0. PubMed PMID:40280976 PubMed Central PMC12032271.
- Shim, J, Tanaka, B, Taub, DG, Mis, MA, Schulman, BR, Snavely, A et al.. Correction of sodium channel mutations in sensory neurons reverses aberrant properties. Brain. 2025; :. doi: 10.1093/brain/awaf155. PubMed PMID:40279376 .