Research
Developmental neurogenetics
Appointments
- Director, Center for Autism Research and Treatment (CART)
- Professor, Neurology
- Psychiatry and Biobehavioral Sciences
- Co-Director, Center for Neurobehavioral Genetics
- Professor in Residence, Tennenbaum Center for the Biology of Creativity
- Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- CTSI
- Genetics & Genomics GPB Home Area
- Neuroscience GPB Home Area
- Research Education, Training, and Career Development Program (CTSI-ED)
Appointments
Dr. Geschwind’s laboratory conducts research in three primary areas of neurogenetics:
- autism and language;
- focal neurodegenerative syndromes;
- and the structural/molecular basis of human cognitive specializations.
Utilizing a multi-pronged approach, he studies normal human and animal model brain patterning to diseases in which language and social communication are disrupted, such as autism.
Publications
- Maddock, RJ, Vlasova, RM, Chen, S, Iosif, AM, Bennett, J, Tanase, C et al.. Altered brain metabolites in male nonhuman primate offspring exposed to maternal immune activation. Brain Behav Immun. 2024; :. doi: 10.1016/j.bbi.2024.07.011. PubMed PMID:39032543 .
- Tian, F, Cheng, Y, Zhou, S, Wang, Q, Monavarfeshani, A, Gao, K et al.. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2024;112 (14):2453-2456. doi: 10.1016/j.neuron.2024.06.009. PubMed PMID:39029995 .
- Tian, F, Cheng, Y, Zhou, S, Wang, Q, Monavarfeshani, A, Gao, K et al.. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2024;112 (14):2452. doi: 10.1016/j.neuron.2024.06.010. PubMed PMID:39029994 .
- Arutiunian, V, Santhosh, M, Neuhaus, E, Sullivan, CAW, Bernier, RA, Bookheimer, SY et al.. A common genetic variant in the Neurexin family member CNTNAP2 is related to language but not communication skills in youth with Autism Spectrum Disorder. Autism Res. 2024; :. doi: 10.1002/aur.3193. PubMed PMID:38984666 .
- Pottier, C, Küçükali, F, Baker, M, Batzler, A, Jenkins, GD, van Blitterswijk, M et al.. Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing. medRxiv. 2024; :. doi: 10.1101/2024.06.24.24309088. PubMed PMID:38978643 PubMed Central PMC11230325.