Research
Developmental neurogenetics
Appointments
- Director, Center for Autism Research and Treatment (CART)
- Professor, Neurology
- Psychiatry and Biobehavioral Sciences
- Co-Director, Center for Neurobehavioral Genetics
- Professor in Residence, Tennenbaum Center for the Biology of Creativity
- Human Genetics
- Member, Bioinformatics GPB Home Area
- Brain Research Institute
- CTSI
- Genetics & Genomics GPB Home Area
- Neuroscience GPB Home Area
- Research Education, Training, and Career Development Program (CTSI-ED)
Appointments
Dr. Geschwind’s laboratory conducts research in three primary areas of neurogenetics:
- autism and language;
- focal neurodegenerative syndromes;
- and the structural/molecular basis of human cognitive specializations.
Utilizing a multi-pronged approach, he studies normal human and animal model brain patterning to diseases in which language and social communication are disrupted, such as autism.
Publications
- Vuong, CK, Weber, A, Seong, P, Matoba, N, Shafie, B, Salinda, A et al.. A single cell multi-omic analysis identifies molecular and gene-regulatory mechanisms dysregulated in the developing Down syndrome neocortex. bioRxiv. 2025; :. doi: 10.1101/2025.06.30.662136. PubMed PMID:40631168 PubMed Central PMC12236736.
- Saloner, R, Staffaroni, AM, Dammer, EB, Johnson, ECB, Paolillo, EW, Wise, A et al.. Author Correction: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Nat Aging. 2025; :. doi: 10.1038/s43587-025-00931-0. PubMed PMID:40624197 .
- Haas, R, Margolis, MP, Wei, A, Yamaguchi, TN, Feng, J, Tran, T et al.. Diverse Genomes, Shared Health: Insights from a Health System Biobank. medRxiv. 2025; :. doi: 10.1101/2025.06.11.25329386. PubMed PMID:40585105 PubMed Central PMC12204455.
- Shade, LMP, Katsumata, Y, Abner, EL, Aung, KZ, Claas, SA, Qiao, Q et al.. Publisher Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. Nat Genet. 2025; :. doi: 10.1038/s41588-024-02046-5. PubMed PMID:40527985 .
- Shade, LMP, Katsumata, Y, Abner, EL, Aung, KZ, Claas, SA, Qiao, Q et al.. Author Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. Nat Genet. 2025; :. doi: 10.1038/s41588-024-02045-6. PubMed PMID:40527984 .