Research
Molecular and cellular and systems mechanisms of learning and memory
Appointments
- Distinguished Professor– Neurobiology, Psychiatry & Biobehavioral Sciences and Psychology
- Director–Integrative Center for Learning and Memory
- Tennenbaum Center for the Biology of Creativity
- Brain Research Institute
- Molecular, Cellular & Integrative Physiology GPB Home Area
- Neuroscience GPB Home Area
Biography
The Silva laboratory is studying the biology of learning and memory. They are interested in the molecular, cellular and circuit processes that underlie the allocation, encoding and storage of information. To accomplish this they are using a variety of techniques including sophisticated molecular and genetic approaches, optical physiology, optogenetics, in vivo imaging and behavioral analysis.
Silva and colleagues have also studied the impact of these mechanisms in animal models of cognitive disorders, including intellectual disabilities. Based on these mechanistic studies, they have developed treatments for Neurofibromatosis type I and Tuberous Sclerosis, that are currently being tested in clinical trials.
The Silva laboratory is also developing bioinformatic strategies for tracking and planning experiments (researchmaps.org).
Publications
- Cremonez, PSG, Kheirodin, A, Perier, JD, Nagaoka, MM, Dunn, TP, Parkins, AJ et al.. Leaf trichome and insecticide interactions relative to Bemisia tabaci (Hemiptera: Aleyrodidae) management in a cotton-cucurbit strip cropping arrangement. J Econ Entomol. 2025; :. doi: 10.1093/jee/toaf321. PubMed PMID:41259812 .
- Araújo, TM, Melo, ECP, Moraes, CL, Magno, L, Muraro, AP, Fonseca, MJMD et al.. Fifth Strategic Plan for the Development of Epidemiology in Brazil (2025-2029). Rev Bras Epidemiol. 2025;28 (suppl 1):e250001supl1. doi: 10.1590/1980-549720250001.supl.1. PubMed PMID:41259487 .
- Silva, AMD, Santana, RLS, Carvalho, EL, Giese, EG. Helminthofauna of Batrachoides surinamensis (Batrachoidiformes: Batrachoididae) from estuaries of the Amazon in Pará, Brazil. Rev Bras Parasitol Vet. 2025;34 (4):e012225. doi: 10.1590/S1984-29612025064. PubMed PMID:41259486 .
- Moniz, MA, Soares, LS, Quitete, JB, Castro, RC, Silva, ACSSD, Barreto, ACM et al.. Professional competencies in environmental health in a nursing curriculum from the perspective of students. Rev Bras Enferm. 2025;78Suppl 3 (Suppl 3):e20240502. doi: 10.1590/0034-7167-2024-0502. PubMed PMID:41259481 .
- Santos, LAC, Silva, AMC, Gomes, RP, Cerboncini, RAS, Santos, NC, Oliveira, AG et al.. Spatial variability of soil organic carbon in native forest and agroforestry system in central Brazilian Amazonia. Braz J Biol. 2025;85 :e297784. doi: 10.1590/1519-6984.297784. PubMed PMID:41259475 .