Research
Molecular and cellular and systems mechanisms of learning and memory
Appointments
- Distinguished Professor– Neurobiology, Psychiatry & Biobehavioral Sciences and Psychology
- Director–Integrative Center for Learning and Memory
- Tennenbaum Center for the Biology of Creativity
- Brain Research Institute
- Molecular, Cellular & Integrative Physiology GPB Home Area
- Neuroscience GPB Home Area
Biography
The Silva laboratory is studying the biology of learning and memory. They are interested in the molecular, cellular and circuit processes that underlie the allocation, encoding and storage of information. To accomplish this they are using a variety of techniques including sophisticated molecular and genetic approaches, optical physiology, optogenetics, in vivo imaging and behavioral analysis.
Silva and colleagues have also studied the impact of these mechanisms in animal models of cognitive disorders, including intellectual disabilities. Based on these mechanistic studies, they have developed treatments for Neurofibromatosis type I and Tuberous Sclerosis, that are currently being tested in clinical trials.
The Silva laboratory is also developing bioinformatic strategies for tracking and planning experiments (researchmaps.org).
Publications
- Silva, AID, Moura, ALA, Galetti, BM, Vieira, BL, Silva, CVDD, Reis, GA et al.. Coprological assessment of domestic carnivores in public areas and health education focused on larva migrans in São Paulo State, Brazil. Rev Bras Parasitol Vet. 2025;34 (4):e009925. doi: 10.1590/S1984-29612025071. PubMed PMID:41370554 .
- Silva, AT, Leal, LA, Ribeiro, MILC, Hilário, JSM, Silva, MMD, Alves, MG et al.. Simulated communication and teamwork scenario for nursing students: construction and validity. Rev Bras Enferm. 2025;78 (suppl 4):e20240600. doi: 10.1590/0034-7167-2024-0600. PubMed PMID:41370542 .
- Gobo, DCM, Lopez, RVM, Silva, AM, Kulcsar, MV. The role of oncology nurse navigators in the outcomes of surgical patients with head and neck cancer. Rev Bras Enferm. 2025;78 (suppl 3):e20240165. doi: 10.1590/0034-7167-2024-0165. PubMed PMID:41370527 .
- Bulizani, IC, Ribeiro, S, Silva, AC, Yamamoto, TT, Leite, RR, Fernandes, H et al.. Tuberculosis detection actions in Primary Health Care during the COVID-19 pandemic. Rev Bras Enferm. 2025;78 (5):e20240389. doi: 10.1590/0034-7167-2024-0389. PubMed PMID:41370451 .
- Campagnani, MO, Campos, WG, Maurício, RM, Madureira, AP, Silva, ACR, Silva, NBM et al.. Tactics of applying entomopathogenic fungi in the control of Plutella xylostella and Brevicoryne brassicae. Braz J Biol. 2025;85 :e300567. doi: 10.1590/1519-6984.300567. PubMed PMID:41370436 .